BRIEF REPORT Primitive Neuroectodermal Tumor (PNET) of the Uterus in a Renal Allograft Patient: A Case Report

Although renal transplantation has dramatically changed the outcome of end stage renal disease, it is associated with significant side effects including opportunistic infections, graft rejection, drug toxicity, and malignancy [1]. The incidence of malignancy after renal transplant has been reported to range from 4% to 18% and may result from pre-existing cancers in recipients, donortransmitted cancers, or de novo malignancies [2,3]. Other predisposing factors for the development of malignancies include immunosuppressive agents, carcinogenic effects of medications, activation of oncogenic viruses, uremia, and antigenic stimulation from the transplant [3,4]. Tumors of the skin and lip tend to be the most common, while non-Hodgkin lymphoma comprises 20% of all neoplasms [3,5]. In this report, we describe a 15year-old female who, 9 years after receiving a living related renal transplant, developed a post-transplant primitive neuroectodermal tumor (PNET) of the uterus.